課程資訊
課程名稱
族群遺傳學
Population Genetics 
開課學期
109-1 
授課對象
生命科學院  基因體與系統生物學學位學程  
授課教師
李承叡 
課號
EEB5045 
課程識別碼
B44EU1570 
班次
 
學分
3.0 
全/半年
半年 
必/選修
選修 
上課時間
星期四2,3,4(9:10~12:10) 
上課地點
生科4C 
備註
本課程以英語授課。最好修過遺傳學或演化生物學。與王弘毅、丁照棣合授
總人數上限:50人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1091EEB5045_ 
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課程概述

See English description 

課程目標
See English description 
課程要求
See English description 
預期每週課後學習時數
 
Office Hours
另約時間 
指定閱讀
Population Genetics, by Matthew B. Hamilton (Wiley-Blackwell, 2009)  
參考書目
Elements of Evolutionary Genetics by Brian Charlesworth and Deborah Charlesworth (2016)
An Introduction to Population Genetics: Theory and Applications, Rasmus Nielsen and Montgomery Slatkin
(Sinauer, 2013)
Population Genetics by Matthew B. Hamilton (2011)
Principles of Population Genetics, (4th Edition) by Daniel L. Hartl and Andrew
G. Clark (Sinauer, 2006)
Population Genetics and Microevolutionary Theory by Alan R. Templeton
(Wiley-Liss, 2006)
Theoretical population genetics, a draft text by Joseph Felsenstein
(http://evolution.genetics.washington.edu/pgbook/pgbook.html)  
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
Week 1
09/17  Introduction/ Thinking like a population geneticist (Ting) 
Week 2
09/24  Genotype frequencies (Ting) 
Week 3
10/01  National Holiday 
Week 4
10/08  Mutation (Ting) 
Week 5
10/15  Genetic drift and effective population size (Lee)  
Week 6
10/22  Population structure and gene flow 1 (Lee) 
Week 7
10/29  Population structure and gene flow 2 (Lee) 
Week 8
11/05  Quantitative trait variation and evolution (Lee) 
Week 9
11/12  Introduction to genetic mapping: QTL and GWAS (Lee) 
Week 10
11/19  Introduction to molecular markers
Case studies (Lee) 
Week 11
11/26  Introduction to Molecular Evolution (Wang)
 
Week 12
12/03  Fundamentals of natural selection (Wang)
 
Week 13
12/10  Further models of natural selection (Wang) 
Week 14
12/17  Population Genomics 1 (Wang) 
Week 15
12/24  Population Genomics 2 (Wang) 
Week 16
12/31  Human Population Genomics (Wang) 
Week 17
1/7  Guest Lecture:
Prof Ko Wen-Ya from Yang Ming University
Detecting genetic ancestry and adaptation in the Taiwanese Han people 
Week 18
1/14  Final week (no class, no exam)